Developing tests to detect antibiotic-resistant E. coli infections
Official title: DEVELOPMENT OF IN VITRO DIAGNOSTICS FOR ANTIMICROBIAL RESISTANCE ESCHERICHIA COLI
Funded at Siemens Healthcare Diagnostics INC. · NIH-10912990 · Data updated 2026-11-12
This study is working on new ways to quickly and accurately find infections caused by tough-to-treat bacteria like antibiotic-resistant E. coli, so that patients can get the right treatment faster.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Siemens Healthcare Diagnostics INC. NIH-funded |
| Lab location | 1 site (Tarrytown, United States) |
| Project start | July 24, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $5,422,657 |
| NIH project number | 75N93023C00025-0-9999-1 |
| Project ID | NIH-10912990 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have or are suspected of having infections caused by antibiotic-resistant E. coli.
✕Less likely to help
Patients with infections caused by non-antibiotic-resistant strains of E. coli may not benefit from this research.
What this research studies
This research focuses on creating advanced diagnostic technologies to identify infections caused by antibiotic-resistant E. coli and other emerging infectious diseases. The approach includes enhancing nucleic acid sequencing methods and improving the detection of proteins in blood and other biofluids. By refining these diagnostic tools, the research aims to provide quicker and more accurate identification of microbial infections, which is crucial for effective treatment.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnoses of antibiotic-resistant infections, improving treatment outcomes for patients.
How similar studies have gone: Previous research has shown promise in developing diagnostic technologies for antimicrobial resistance, indicating a potential for success in this area.
Where this research is happening
-
Siemens Healthcare Diagnostics INC.
Tarrytown, United States Active
Researchers
- Principal investigator: Sampath, Rangarajan — Siemens Healthcare Diagnostics INC.
- Study coordinator: Sampath, Rangarajan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.