Developing technology to identify and measure sugar structures that affect viral infections
Enabling Technology to Screen and Quantify Sialylated Structures for Activity Against Viral Enzymes and Receptors
['FUNDING_R01'] · WEST VIRGINIA UNIVERSITY · NIH-10757661
This study is looking at how certain sugar molecules in our bodies interact with viruses, and it's trying to find new ways to stop these viruses from attaching to our cells, which could lead to better treatments for people dealing with viral infections.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEST VIRGINIA UNIVERSITY (nih funded) |
| Locations | 1 site (MORGANTOWN, UNITED STATES) |
| Trial ID | NIH-10757661 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how specific sugar molecules, known as sialylated glycans, interact with viruses and their receptors. By using innovative techniques, the researchers aim to identify these interactions and develop new inhibitors that can block viral binding. The approach involves advanced methods like capillary electrophoresis to analyze these sugar structures, which could lead to more effective treatments for viral infections. Patients may benefit from new therapies that target these interactions, potentially improving outcomes for those affected by viral diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with viral infections, particularly those affected by influenza or similar viruses.
Not a fit: Patients who do not have viral infections or those with conditions unrelated to viral activity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new antiviral treatments that effectively inhibit viral infections.
How similar studies have performed: Previous research has shown promise in developing inhibitors targeting viral interactions, suggesting potential for success in this area.
Where this research is happening
MORGANTOWN, UNITED STATES
- WEST VIRGINIA UNIVERSITY — MORGANTOWN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HOLLAND, LISA A — WEST VIRGINIA UNIVERSITY
- Study coordinator: HOLLAND, LISA A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.