Developing targeted vaccines to enhance antibody responses

Creating high-resolution, epitope-focused vaccines

NIH-funded research Stanford University · NIH-10904972

This study is working on new vaccines that aim to train your immune system to fight off viruses like HIV, Ebola, and the flu by focusing on specific parts of these viruses, so you can have better protection against different strains.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-10904972 on NIH RePORTER

What this research studies

This research aims to create innovative vaccines that specifically target certain parts of viruses, known as epitopes, to generate a strong immune response. By focusing on these key areas, the vaccines are designed to produce neutralizing antibodies that can effectively combat infectious diseases like HIV, Ebola, and influenza. The approach utilizes broadly neutralizing monoclonal antibodies as a foundation, which have shown promise in clinical trials. If successful, this method could lead to vaccines that provide broad protection against various strains of these viruses.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at risk for infections caused by HIV, Ebola, or influenza, who may benefit from enhanced vaccine responses.

Not a fit: Patients with existing immunity or those who have already been vaccinated against these viruses may not receive additional benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of more effective vaccines that provide better protection against infectious diseases.

How similar studies have performed: Other research has shown promise in using monoclonal antibodies for vaccine development, indicating that this approach has potential for success.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Communicable Diseases
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.