Developing targeted therapies for aggressive prostate cancer
Multimodal dendrimer theranostics targeting aggressive subtypes of prostate cancer
['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-10977964
This study is exploring a new way to diagnose and treat aggressive prostate cancer by using special agents that target a specific protein in the cancer cells, which could lead to more effective treatments with fewer side effects for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-10977964 on ClinicalTrials.gov |
What this research studies
This research aims to create a new platform for diagnosing and treating aggressive prostate cancer using specialized agents that target a specific protein associated with the disease. By utilizing poly(amidoamine) dendrimers, the study focuses on delivering both imaging and therapeutic agents directly to cancer cells, which could improve treatment effectiveness while minimizing side effects. The approach involves advanced imaging techniques and targeted therapies that have shown promise in previous trials. Patients may benefit from more precise and effective treatment options tailored to their specific cancer characteristics.
Who could benefit from this research
Good fit: Ideal candidates for this research are men diagnosed with aggressive prostate cancer, particularly those with metastatic disease expressing prostate-specific membrane antigen (PSMA).
Not a fit: Patients with non-aggressive prostate cancer or those who do not express PSMA may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and less toxic treatment options for patients with aggressive prostate cancer.
How similar studies have performed: Previous research has shown success with similar PSMA-targeted therapies, indicating a promising avenue for further development.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: POMPER, MARTIN G — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: POMPER, MARTIN G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: American Cancer Society