Developing targeted agents for cancer prevention and interception
Cancer Prevention-Interception Targeted Agent Discovery Program at Fox Chase Cancer Center
['FUNDING_OTHER'] · RESEARCH INST OF FOX CHASE CAN CTR · NIH-10909960
This study is looking for ways to help people with a family history of cancer by finding new treatments that can stop cancer before it starts, and it involves patients in testing these promising new options.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RESEARCH INST OF FOX CHASE CAN CTR (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10909960 on ClinicalTrials.gov |
What this research studies
This research focuses on identifying and developing targeted agents that can prevent or intercept cancer in individuals with hereditary cancer predispositions. A multidisciplinary team at Fox Chase Cancer Center is utilizing advanced technologies to understand the molecular changes that lead to precancerous lesions and early tumor development. The project aims to create a pipeline for developing effective interventions tailored to high-risk populations, leveraging a large database of families and mutation carriers. Patients may be involved in studies that assess the efficacy of these new agents in preventing cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with hereditary cancer syndromes or those identified as high-risk for developing cancer due to genetic factors.
Not a fit: Patients without hereditary cancer predispositions or those at low risk for cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new targeted therapies that significantly reduce the risk of cancer in high-risk individuals.
How similar studies have performed: Previous research has shown promise in developing targeted therapies for cancer prevention, indicating that this approach could yield significant advancements.
Where this research is happening
PHILADELPHIA, UNITED STATES
- RESEARCH INST OF FOX CHASE CAN CTR — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CLAPPER, MARGIE L. — RESEARCH INST OF FOX CHASE CAN CTR
- Study coordinator: CLAPPER, MARGIE L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Barrett Syndrome