Developing Sudaxine to prevent breathing problems caused by opioids after surgery
Development of Sudaxine for the Treatment of Opioid Induced Respiratory Depression (OIRD) in the Peri-operative Hospital Setting
This study is testing a new medication called Sudaxine, which is designed to help prevent breathing problems caused by opioid painkillers during and after surgery, so patients can feel safe and comfortable without losing pain relief.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Atelerix Life Sciences INC. NIH-funded |
| Lab location | 1 site (Indianapolis, UNITED STATES) |
| Project ID | NIH-10706602 on NIH RePORTER |
What this research studies
This research focuses on creating a new medication called Sudaxine, which aims to prevent respiratory depression caused by opioids in patients undergoing surgery. Opioids are commonly used for pain relief during and after surgical procedures, but they can sometimes lead to dangerous breathing issues. Sudaxine works by targeting specific pathways in the body to reverse these breathing problems without affecting the pain relief provided by opioids. The research has already shown promising results in early tests, indicating that Sudaxine is safe and effective.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults undergoing surgical procedures who require opioid pain management.
Not a fit: Patients who are not undergoing surgery or who do not require opioid pain relief may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a safer way for patients to manage pain after surgery without the risk of respiratory depression.
How similar studies have performed: Other research has shown success with similar approaches in managing opioid-related side effects, but Sudaxine represents a novel solution specifically targeting respiratory depression.
Where this research is happening
Indianapolis, UNITED STATES
- Atelerix Life Sciences INC. — Indianapolis, United States (Active)
Researchers
- Principal investigator: Bates, James N — Atelerix Life Sciences INC.
- Study coordinator: Bates, James N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.