NIH-funded research R21 grant

Developing stronger and more durable dental materials for better tooth restoration

Official title: Uniquely high conversion and mechanically robust composite restorative materials for functionally elevated performance

Funded at University of Colorado Denver · NIH-10646845 · Data updated 2026-11-12

This study is working on new dental materials that make fillings and other repairs for tooth decay stronger and longer-lasting, so you can enjoy better dental work that doesn’t need to be replaced as often.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startSeptember 5, 2023
Project endSeptember 4, 2025
Funding year2023
Award (this year)$441,500
NIH project number1R21DE032797-01
Project IDNIH-10646845 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals requiring dental restorations due to tooth decay or damage.

Less likely to help

Patients with no need for dental restorations or those who have already received treatment with existing materials may not benefit from this research.

What this research studies

This research focuses on creating advanced dental materials that enhance the strength and durability of restorations used in treating tooth decay. By utilizing innovative hydrogen bonding techniques in polymer chemistry, the project aims to develop new composite materials that can withstand wear and provide better performance than current options. Patients can benefit from these materials through improved dental restorations that last longer and require fewer replacements. The research involves testing these materials under various conditions to ensure their effectiveness and safety.

Why it matters

Potential benefit: If successful, this research could lead to dental materials that significantly improve the longevity and performance of tooth restorations.

How similar studies have gone: Previous research has shown promising results in enhancing dental materials through innovative polymer chemistry, indicating potential for success in this approach.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Stansbury, Jeffrey W. — University of Colorado Denver
  • Study coordinator: Stansbury, Jeffrey W.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.