Developing specialized antibodies for studying diseases in nonhuman primates

Magnani_P40_Applied Research

NIH-funded research Univ of Massachusetts Med Sch Worcester · NIH-10935287

This study is all about making special antibodies that work better in nonhuman primates, helping researchers learn more about diseases and find new treatments without causing unwanted immune reactions.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of Massachusetts Med Sch Worcester NIH-funded
Lab location1 site (Worcester, United States)
Project IDNIH-10935287 on NIH RePORTER

What this research studies

This research focuses on creating and refining antibodies that are specifically designed for use in nonhuman primate studies, which are crucial for understanding disease mechanisms and developing treatments. The team employs advanced techniques to modify these antibodies, making them less likely to provoke immune reactions in the primate models. By enhancing the compatibility of these antibodies, the research aims to improve the quality and reliability of biomedical studies conducted on nonhuman primates. This work is essential for advancing our understanding of various diseases and could lead to significant breakthroughs in treatment.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research include individuals with autoimmune diseases who may eventually benefit from advancements in treatment derived from nonhuman primate studies.

Not a fit: Patients with conditions unrelated to autoimmune diseases or those not involved in biomedical research may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for autoimmune diseases and other conditions by improving the tools available for biomedical research.

How similar studies have performed: Previous research has shown success in developing specialized antibodies for biomedical applications, indicating that this approach has potential for significant advancements.

Where this research is happening

Worcester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autoimmune Diseasesautoimmune disorderautoimmunity disease
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.