Developing software tools to analyze single-cell genomic data
Official title: New software tools for differential analysis of single-cell genomics perturbation experiments
Funded at University of Washington · NIH-10933558 · Data updated 2026-11-12
This study is all about making new software that helps scientists look at tiny details in our cells to understand how things like genetics and the environment affect how cells work, which could lead to better insights into diseases.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 22, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $662,862 |
| NIH project number | 5R01HG012761-02 |
| Project ID | NIH-10933558 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve complex cellular changes, such as cancer or genetic disorders.
✕Less likely to help
Patients with stable, non-progressive conditions that do not involve significant cellular changes may not benefit from this research.
What this research studies
This research focuses on creating new software tools that will help scientists analyze complex data from single-cell genomics experiments. By utilizing advanced techniques like ATAC sequencing, the project aims to better understand how various factors, such as genetic changes or environmental influences, affect cell types and their functions within tissues. The tools developed will enable researchers to compare and interpret large datasets, ultimately enhancing our understanding of disease progression and development at a cellular level.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for diagnosing and treating diseases by providing deeper insights into cellular behavior and interactions.
How similar studies have gone: Other research in the field of single-cell genomics has shown promising results, indicating that the development of software tools for data analysis can significantly enhance our understanding of cellular processes.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Trapnell, Bruce Colston — University of Washington
- Study coordinator: Trapnell, Bruce Colston
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.