Developing smarter brain-machine interfaces that communicate with users

Ghost in the Machine: Melding Brain, Computer and Behavior

NIH-funded research University of Pennsylvania · NIH-10924034

This study is exploring new ways for brain-machine devices to talk to you and learn from your thoughts and feelings, with the hope of making treatments for neurological conditions more effective and tailored to your needs.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10924034 on NIH RePORTER

What this research studies

This research focuses on creating advanced brain-machine interfaces that can interact with users by asking questions and learning from their thoughts and feelings. By integrating peripheral sensors with implantable devices, the goal is to enhance the effectiveness of these devices in managing neurological conditions. The approach involves a two-way communication where both the device and the user can teach and learn from each other, ultimately aiming to improve health outcomes and quality of life. This innovative method seeks to personalize therapy based on real-time feedback from the user.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with neurological disorders such as epilepsy who may benefit from implantable devices.

Not a fit: Patients without neurological conditions or those who do not require implantable devices may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for neurological conditions by enabling devices to adapt to individual patient needs.

How similar studies have performed: While there has been significant investment in brain-computer interfaces, this approach of reciprocal communication between devices and users is novel and has not been extensively tested.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.