Developing smart coatings to prevent infections in medical devices
Plasma-initiated Cross-linked Nanocoatings asAnti-infection Agents
['FUNDING_R01'] · FAIRLEIGH DICKINSON UNIVERSITY · NIH-10885154
This study is working on new, safe coatings for catheters that can help prevent infections caused by tough bacteria, using a special technology that makes the coatings smart enough to detect and fight off germs, all without using antibiotics.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FAIRLEIGH DICKINSON UNIVERSITY (nih funded) |
| Locations | 1 site (TEANECK, UNITED STATES) |
| Trial ID | NIH-10885154 on ClinicalTrials.gov |
What this research studies
This research focuses on creating innovative, antibiotic-free coatings for medical devices, particularly catheters, to combat infections caused by antibiotic-resistant bacteria. By utilizing argon plasma technology, the team is developing cross-linked nanocoatings that can effectively target and eliminate harmful bacteria and biofilms. These coatings are designed to be biocompatible and can sense bacterial presence, triggering a response to prevent infections. The approach aims to reduce the high rates of medical-device-associated infections and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients who require the use of catheters or other medical implants and are at risk for infections.
Not a fit: Patients who do not require medical devices or have no risk of infection from such devices may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of infections related to medical devices, leading to better health outcomes for patients.
How similar studies have performed: Previous research has shown promise in using similar nanocoating technologies to combat bacterial infections, indicating potential for success in this novel approach.
Where this research is happening
TEANECK, UNITED STATES
- FAIRLEIGH DICKINSON UNIVERSITY — TEANECK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TRABA, CHRISTIAN — FAIRLEIGH DICKINSON UNIVERSITY
- Study coordinator: TRABA, CHRISTIAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.