Developing small molecules to block a protein linked to breast cancer spread
Small Molecule Inhibitors of the Inflammatory Cytokine Oncostatin M
This study is working on developing new medications that can help stop the spread of breast cancer by blocking a specific protein called oncostatin M, which is linked to cancer growth, with the hope of improving treatment options for patients.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boise State University NIH-funded |
| Lab location | 1 site (Boise, United States) |
| Project ID | NIH-10438068 on NIH RePORTER |
What this research studies
This research focuses on creating small molecule inhibitors that target and block the inflammatory cytokine oncostatin M (OSM), which is associated with breast cancer metastasis. By inhibiting OSM signaling, the project aims to prevent the early stages of tumor spread, potentially improving outcomes for patients diagnosed with breast cancer. The approach involves synthesizing these inhibitors and testing their effectiveness through advanced biological assays. If successful, this could lead to new FDA-approved treatments that protect against the progression of breast cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with breast cancer, particularly those at risk of metastasis due to high levels of OSM.
Not a fit: Patients with non-cancerous conditions or those without elevated OSM levels may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new therapeutic option that significantly reduces the risk of breast cancer metastasis.
How similar studies have performed: While the approach of targeting OSM is promising, it is relatively novel and has not been extensively tested in clinical settings.
Where this research is happening
Boise, United States
- Boise State University — Boise, United States (Active)
Researchers
- Principal investigator: Warner, Don L — Boise State University
- Study coordinator: Warner, Don L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.