Developing scaffolds to help regenerate craniofacial bone tissue
Official title: Bioactive cellulose-nanodiamond (CeND) scaffolds for applications in craniofacial bone tissue regeneration
Funded at University of Puerto Rico Rio Piedras · NIH-10467026 · Data updated 2026-11-12
This study is testing a new material made from tiny fibers to help heal and grow bone in the face, and it's designed for people who need help with bone regeneration after injuries or surgeries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Puerto Rico Rio Piedras NIH-funded |
| Lab location | 1 site (San Juan, United States) |
| Project start | September 1, 2019 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $372,500 |
| NIH project number | 5SC1GM127220-04 |
| Project ID | NIH-10467026 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with craniofacial bone defects or conditions requiring bone regeneration.
✕Less likely to help
Patients with non-craniofacial bone issues or those who do not require bone regeneration may not benefit from this research.
What this research studies
This research focuses on creating a new type of bioactive scaffold made from cellulose-nanodiamond fibers to aid in the regeneration of craniofacial bone tissue. The scaffolds are designed to be semi-rigid and will be produced using an electrospinning technique. By incorporating growth and adhesion factors, the researchers aim to enhance the healing process and improve the rate at which bone tissue regenerates. The effectiveness of these scaffolds will be tested in laboratory models and in animal studies to assess their biocompatibility and ability to promote bone growth.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients needing craniofacial bone regeneration, potentially enhancing recovery and outcomes.
How similar studies have gone: Other research has shown promise in using bioactive scaffolds for tissue regeneration, indicating a potential for success in this approach.
Where this research is happening
-
University of Puerto Rico Rio Piedras
San Juan, United States Active
Researchers
- Principal investigator: Nicolau, Eduardo — University of Puerto Rico Rio Piedras
- Study coordinator: Nicolau, Eduardo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.