Developing safe, non-addictive treatments for chronic pain.

STSS Aspire Heal Task Order 10

NIH-funded research Axle Informatics, LLC · NIH-10950010

This study is looking for new, safe ways to help people with chronic pain feel better without the risk of addiction, and it invites patients to be part of this exciting journey to find better pain relief options.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionAxle Informatics, LLC NIH-funded
Lab location1 site (North Bethesda, United States)
Project IDNIH-10950010 on NIH RePORTER

What this research studies

This research focuses on finding new, safe, and effective treatments for the millions of Americans suffering from chronic pain, particularly in light of the opioid crisis. The approach involves identifying novel drug targets and utilizing advanced technologies such as integrated chemistry databases and predictive algorithms to develop non-addictive pain relief options. By leveraging human-based, physiologically relevant systems, the research aims to create drugs that can alleviate pain without the risk of addiction or overdose. Patients may have the opportunity to contribute to this innovative drug development process.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals experiencing chronic pain who are seeking non-addictive treatment options.

Not a fit: Patients who do not experience chronic pain or are not seeking alternatives to opioid medications may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide patients with safer alternatives to opioids for managing chronic pain.

How similar studies have performed: Previous research efforts have shown promise in developing non-addictive pain treatments, but this approach aims to innovate further in a critical area of need.

Where this research is happening

North Bethesda, United States

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.