Developing safe, non-addictive treatments for chronic pain.
Official title: STSS Aspire Heal Task Order 10
Funded at Axle Informatics, LLC · NIH-10950010 · Data updated 2026-11-12
This study is looking for new, safe ways to help people with chronic pain feel better without the risk of addiction, and it invites patients to be part of this exciting journey to find better pain relief options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Axle Informatics, LLC NIH-funded |
| Lab location | 1 site (North Bethesda, United States) |
| Project start | September 18, 2023 |
| Project end | September 17, 2025 |
| Funding year | 2023 |
| Award (this year) | $3,347,069 |
| NIH project number | 75N95023D00001-0-759502300017-1 |
| Project ID | NIH-10950010 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals experiencing chronic pain who are seeking non-addictive treatment options.
✕Less likely to help
Patients who do not experience chronic pain or are not seeking alternatives to opioid medications may not benefit from this research.
What this research studies
This research focuses on finding new, safe, and effective treatments for the millions of Americans suffering from chronic pain, particularly in light of the opioid crisis. The approach involves identifying novel drug targets and utilizing advanced technologies such as integrated chemistry databases and predictive algorithms to develop non-addictive pain relief options. By leveraging human-based, physiologically relevant systems, the research aims to create drugs that can alleviate pain without the risk of addiction or overdose. Patients may have the opportunity to contribute to this innovative drug development process.
Why it matters
Potential benefit: If successful, this research could provide patients with safer alternatives to opioids for managing chronic pain.
How similar studies have gone: Previous research efforts have shown promise in developing non-addictive pain treatments, but this approach aims to innovate further in a critical area of need.
Where this research is happening
-
Axle Informatics, LLC
North Bethesda, United States Active
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.