Developing personalized treatments for gum disease in older adults
Personalized Strategies for Periodontal Tissue Regeneration - A Converged Biofabrication Approach
This study is exploring new ways to help older adults with gum disease by creating special supports that encourage healing and bone growth in their gums.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11077799 on NIH RePORTER |
What this research studies
This research focuses on creating personalized strategies to regenerate periodontal tissue affected by gum disease, particularly in individuals over 65. The approach involves using advanced fabrication techniques to develop specialized scaffolds that promote bone growth and support the healing of gum tissue. By tailoring these scaffolds to the specific needs of patients, the research aims to improve outcomes for those suffering from severe bone loss due to periodontitis. The effectiveness of these strategies will be tested in clinically relevant animal models before potential application in human patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those over the age of 65, who are experiencing severe periodontal issues.
Not a fit: Patients with mild gum disease or those who do not have significant bone loss may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that prevent tooth loss and improve oral health in older adults suffering from gum disease.
How similar studies have performed: Previous research has shown promise in using advanced fabrication techniques for tissue regeneration, suggesting potential success for this novel approach.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Bottino, Marco C — University of Michigan at Ann Arbor
- Study coordinator: Bottino, Marco C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.