Developing personalized therapies for cystic fibrosis
Personalized Cystic Fibrosis Therapy and Research Center
This study is working on creating special lab models using cells from cystic fibrosis patients to better understand how a key protein works and to help develop personalized treatments just for them.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-10923874 on NIH RePORTER |
What this research studies
This research focuses on creating personalized model systems using patient-specific cultures derived from intestinal cells and stem cells. These models will help researchers study the function of the CFTR protein, which is crucial for fluid balance in the body, and develop tailored treatment options for cystic fibrosis patients. The project aims to provide resources and training to researchers worldwide, facilitating advancements in personalized therapies for cystic fibrosis. By banking and characterizing these models, the research seeks to improve understanding and treatment of this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cystic fibrosis who can provide samples for developing personalized models.
Not a fit: Patients without a diagnosis of cystic fibrosis or those who cannot provide the necessary biological samples may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatment options for cystic fibrosis patients.
How similar studies have performed: Other research has shown promise in using patient-specific models for personalized medicine, indicating a potential for success in this approach.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Helmrath, Michael a. — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Helmrath, Michael a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.