Developing personalized brain stimulation for mental health treatment

Closing the loop: development of real-time, personalized brain stimulation

NIH-funded research Stanford University · NIH-10744211

This study is exploring a new way to make brain treatments more personal and effective for people with mental health issues like depression and OCD by using special brain scans to tailor the therapy just for you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-10744211 on NIH RePORTER

What this research studies

This research focuses on creating targeted and individualized brain stimulation treatments for mental health disorders, which affect a significant portion of the population. It utilizes repetitive transcranial magnetic stimulation (rTMS) combined with electroencephalography (EEG) to identify biomarkers that can optimize treatment for conditions like depression and OCD. By monitoring brain activity, the goal is to personalize rTMS therapy, improving its effectiveness and response rates for patients. This innovative approach aims to move away from the one-size-fits-all model of psychiatric treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals suffering from depression, OCD, PTSD, or substance use disorders who are seeking innovative treatment options.

Not a fit: Patients with mental health disorders who do not respond to brain stimulation therapies or those who are not eligible for rTMS may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatments for mental health disorders, improving patient outcomes significantly.

How similar studies have performed: Previous research has shown promise in using biomarkers to optimize rTMS treatment, indicating that this approach could lead to significant advancements in mental health therapies.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.