Developing personalized biomarkers for melanoma treatment
NYU Melanoma SPORE
This study is looking to make melanoma treatments better by finding special markers that can help doctors predict how well patients will respond to certain immune therapies, so they can choose the best options with fewer side effects.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11192524 on NIH RePORTER |
What this research studies
This research focuses on improving the treatment of melanoma by developing personalized biomarkers that can predict how patients will respond to immune checkpoint inhibition therapies. By integrating these biomarkers into clinical care, the goal is to optimize treatment selection and minimize toxicity for patients. The project aims to validate these biomarkers in the adjuvant setting, where immunotherapies are increasingly used. Researchers have already made significant progress, including the identification of auto-antibody signatures that can predict treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are melanoma patients who are considering or currently undergoing immune checkpoint inhibition therapy.
Not a fit: Patients with melanoma who are not eligible for immune checkpoint inhibition therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatment options for melanoma patients.
How similar studies have performed: Other research has shown success in developing biomarkers for predicting treatment responses in cancer therapies, making this approach promising.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Osman, Iman — New York University School of Medicine
- Study coordinator: Osman, Iman
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.