Developing non-addictive treatments for pain management
EPPIC-Net Pain Research - Application for Clinical Trial and Related Activities (OT2)
This study is looking for people with knee pain from osteoarthritis to try a new non-addictive medication that could help manage their pain without the risks of opioids.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11111675 on NIH RePORTER |
What this research studies
This research focuses on creating and testing new non-addictive treatments for managing pain, particularly in patients suffering from conditions like knee osteoarthritis. It is part of a larger initiative aimed at reducing opioid addiction linked to pain management. The project involves conducting clinical trials to evaluate the safety and effectiveness of a novel drug, CNTX-6970, in patients with moderate to severe knee pain. Participants will be closely monitored and assessed to gather valuable data on their pain relief and overall health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for participation include adults aged 21 and older who experience moderate to severe knee osteoarthritis pain.
Not a fit: Patients with pain conditions that are not related to knee osteoarthritis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide patients with safer alternatives to opioids for pain management.
How similar studies have performed: Previous research has shown promise in developing non-addictive pain treatments, making this approach both relevant and potentially impactful.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Fava, Maurizio — Massachusetts General Hospital
- Study coordinator: Fava, Maurizio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.