Developing new vaccines to stop the spread of pneumonia-causing bacteria.
Targeting Pneumococcal Transmission
This study is looking at how the bacteria that can cause pneumonia spreads among kids, using baby mice to find out which genes help it spread, with the hope of discovering new vaccine targets to help stop the infection from spreading.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10766129 on NIH RePORTER |
What this research studies
This research focuses on understanding how the bacteria Streptococcus pneumoniae spreads from person to person, particularly in children. By using a specially designed infant mouse model, researchers aim to identify specific genes that contribute to the bacteria's transmission. The study involves screening genetic variations to discover potential targets for new vaccines that could effectively interrupt the transmission cycle. This approach is based on insights gained from years of childhood immunization efforts.
Who could benefit from this research
Good fit: Ideal candidates for this research are unvaccinated children aged 0-11 years who are at risk of pneumococcal infections.
Not a fit: Patients who are already vaccinated against pneumococcal disease may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of vaccines that significantly reduce the spread of pneumonia in children.
How similar studies have performed: Previous research has shown promise in vaccine development targeting bacterial transmission, indicating that this approach could yield significant advancements.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Weiser, Jeffrey Neal — New York University School of Medicine
- Study coordinator: Weiser, Jeffrey Neal
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.