Developing new vaccines to protect against pandemics
Translational Immunology Core
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10863340
This study is working on developing better vaccines for viruses that could cause pandemics, and it aims to find ways to make these vaccines safer and more effective for people like you by learning from animal models and lab-grown human tissues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-10863340 on ClinicalTrials.gov |
What this research studies
This research focuses on creating effective vaccines for virus families that pose a serious pandemic threat. It aims to bridge the gap between small animal models and human trials by collecting detailed immunogenicity and safety data from non-human primates and human organoid models. By identifying common features that promote protective immunity, the project seeks to enhance the success rate of vaccine candidates in clinical trials. Patients may benefit from the insights gained in this research, which could lead to the development of vaccines that effectively protect against emerging infectious diseases.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals at risk for infectious diseases or those interested in vaccine development.
Not a fit: Patients with conditions unrelated to infectious diseases or those who are not at risk for pandemics may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective vaccines that protect patients from serious infectious diseases and pandemics.
How similar studies have performed: Previous research has shown promise in vaccine development using similar translational approaches, although this specific methodology is innovative.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WAGAR, LISA — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: WAGAR, LISA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.