Developing new vaccines to protect against pandemics
Official title: Translational Immunology Core
Funded at University of California-Irvine · NIH-10863340 · Data updated 2026-11-12
This study is working on developing better vaccines for viruses that could cause pandemics, and it aims to find ways to make these vaccines safer and more effective for people like you by learning from animal models and lab-grown human tissues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | August 20, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $5,972,985 |
| NIH project number | 1U19AI181968-01 |
| Project ID | NIH-10863340 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals at risk for infectious diseases or those interested in vaccine development.
✕Less likely to help
Patients with conditions unrelated to infectious diseases or those who are not at risk for pandemics may not receive direct benefits from this research.
What this research studies
This research focuses on creating effective vaccines for virus families that pose a serious pandemic threat. It aims to bridge the gap between small animal models and human trials by collecting detailed immunogenicity and safety data from non-human primates and human organoid models. By identifying common features that promote protective immunity, the project seeks to enhance the success rate of vaccine candidates in clinical trials. Patients may benefit from the insights gained in this research, which could lead to the development of vaccines that effectively protect against emerging infectious diseases.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective vaccines that protect patients from serious infectious diseases and pandemics.
How similar studies have gone: Previous research has shown promise in vaccine development using similar translational approaches, although this specific methodology is innovative.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Wagar, Lisa — University of California-Irvine
- Study coordinator: Wagar, Lisa
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.