Developing new vaccines to protect against influenza.

Collaborative Influenza Vaccine Innovation Centers (CIVICs): Component C: Clinical Core

NIH-funded research Duke University · NIH-11041317

This study is looking for people to help test new flu vaccines that could protect against different types of the virus, and it involves some volunteers being exposed to the flu to see how well the vaccines work.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11041317 on NIH RePORTER

What this research studies

This research focuses on creating and testing innovative influenza vaccines through carefully designed clinical trials. Patients may participate in these trials, which assess the safety and effectiveness of new vaccine candidates. The approach includes human challenge studies, where volunteers may be exposed to the virus to evaluate the vaccine's protective effects. The goal is to develop a universal flu vaccine that can provide broader protection against various strains of the influenza virus.

Who could benefit from this research

Good fit: Ideal candidates for participation include healthy adults who are willing to engage in clinical trials for influenza vaccines.

Not a fit: Patients with severe allergies to vaccine components or those with compromised immune systems may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a more effective and long-lasting vaccine against influenza, reducing the incidence of flu-related illnesses.

How similar studies have performed: Previous research has shown promise in developing innovative vaccine approaches, but this specific universal influenza vaccine strategy is still being explored.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.