Developing new treatments to slow down age-related diseases
Core C - Drug Discovery and Development Core (DDDC)
This study is looking at how aging cells stop working properly and how that affects our health, with the goal of finding new treatments that could help people feel better as they get older.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11079500 on NIH RePORTER |
What this research studies
This research focuses on understanding cellular senescence, which is the process by which cells lose their ability to divide and function properly as we age. By investigating the role of senescent cells in various age-related health issues, the research aims to develop therapeutic strategies that can slow or prevent these diseases. The approach includes using genetic and pharmacologic methods to eliminate senescent cells and testing new drugs designed to target these cells specifically. Patients may benefit from potential new treatments that improve health outcomes related to aging.
Who could benefit from this research
Good fit: Ideal candidates for participation are older adults experiencing age-related health issues, such as skeletal fragility or muscle loss.
Not a fit: Patients who are not experiencing age-related diseases or are younger adults may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that significantly improve the quality of life for older adults by addressing age-related diseases.
How similar studies have performed: Previous research has shown promise in targeting senescent cells for age-related conditions, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Robbins, Paul D. — Mayo Clinic Rochester
- Study coordinator: Robbins, Paul D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.