Developing new treatments to protect healthy tissues during cancer radiation therapy
Novel extremophile-inspired radioprotectants
['FUNDING_OTHER'] · UNIVERSITY OF IOWA · NIH-10909534
This study is exploring new RNA treatments that could help protect healthy tissues from radiation damage in cancer patients, aiming to reduce side effects like mouth and bowel issues, so you can feel better during your treatment.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF IOWA (nih funded) |
| Locations | 1 site (IOWA CITY, UNITED STATES) |
| Trial ID | NIH-10909534 on ClinicalTrials.gov |
What this research studies
This research focuses on creating innovative RNA-based therapies to protect healthy tissues from damage caused by radiation therapy in cancer patients. By utilizing extremophile proteins and advanced delivery methods, the project aims to specifically target and deliver protective nucleic acids to affected tissues. This approach seeks to minimize common side effects such as oral mucositis and proctitis, which can lead to severe complications and treatment interruptions. The goal is to enhance the effectiveness of radiation therapy while improving the overall quality of life for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients who are undergoing radiation therapy and are at risk of experiencing radiation-induced injuries.
Not a fit: Patients who are not undergoing radiation therapy or those with conditions unrelated to radiation exposure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the side effects of radiation therapy, leading to better treatment adherence and improved patient outcomes.
How similar studies have performed: While the approach of using RNA-based therapies for radiation protection is innovative, similar strategies have shown promise in other contexts, indicating potential for success.
Where this research is happening
IOWA CITY, UNITED STATES
- UNIVERSITY OF IOWA — IOWA CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BYRNE, JAMES DONALD — UNIVERSITY OF IOWA
- Study coordinator: BYRNE, JAMES DONALD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Patient, Disease, Disorder, Infection, Injury