Developing new treatments to prevent relapse in substance use disorders.
MRI GLOBAL - MILLER DMFP
This study is testing new medications to help people with substance use disorders by looking at how these drugs can change brain activity and reduce cravings, all while using advanced imaging technology to see how well they work.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Midwest Research Institute NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project ID | NIH-10910952 on NIH RePORTER |
What this research studies
This research focuses on creating nonmuscle II inhibitors aimed at preventing relapse in individuals struggling with substance use disorders. By utilizing advanced magnetic resonance imaging (MRI) techniques, the study seeks to understand how these inhibitors can affect brain function and behavior related to substance use. Patients may be involved in trials that assess the effectiveness of these new treatments in reducing cravings and preventing relapse. The approach combines innovative drug development with cutting-edge imaging technology to provide insights into treatment efficacy.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a history of substance use disorders who are currently in recovery or at risk of relapse.
Not a fit: Patients who are not currently experiencing substance use issues or those who have not previously struggled with substance use disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new medications that significantly reduce the risk of relapse for individuals recovering from substance use disorders.
How similar studies have performed: Other research has shown promise in using similar approaches to develop treatments for substance use disorders, indicating potential for success in this area.
Where this research is happening
Kansas City, United States
- Midwest Research Institute — Kansas City, United States (Active)
Researchers
- Principal investigator: Slade, Desmond — Midwest Research Institute
- Study coordinator: Slade, Desmond
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.