Developing new treatments to counteract cyanide poisoning
Official title: Platinum Based Countermeasures and Combinations with Protective Agents
Funded at Purdue University · NIH-10953968 · Data updated 2026-11-12
This study is working on new treatments to help people who have been exposed to cyanide, using animal models to find safer and more effective ways to neutralize the poison and improve recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Purdue University NIH-funded |
| Lab location | 1 site (West Lafayette, United States) |
| Project start | August 20, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $590,302 |
| NIH project number | 1UG3NS134957-01A1 |
| Project ID | NIH-10953968 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would include individuals at risk of cyanide exposure, such as first responders, industrial workers, or those in environments where chemical exposure is a concern.
✕Less likely to help
Patients who have already experienced severe cyanide poisoning and are beyond the point of effective intervention may not benefit from this research.
What this research studies
This research focuses on creating effective countermeasures against cyanide exposure using various animal models. The team aims to develop next-generation platinum-based agents that can safely neutralize cyanide and evaluate their effectiveness in combination with other protective agents. By addressing the limitations of current treatments, this project seeks to improve survival rates and reduce long-term health effects from cyanide poisoning. The research will involve rigorous testing and evaluation to ensure the safety and efficacy of these new interventions.
Why it matters
Potential benefit: If successful, this research could provide life-saving treatments for individuals exposed to cyanide, significantly improving their chances of recovery.
How similar studies have gone: While there have been advancements in countermeasures for chemical exposures, this specific approach using platinum-based agents is relatively novel and has not been extensively tested in this context.
Where this research is happening
-
Purdue University
West Lafayette, United States Active
Researchers
- Principal investigator: Davisson, Vincent Jo — Purdue University
- Study coordinator: Davisson, Vincent Jo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.