Developing new treatments for tuberculosis
Design, Syntheses and Studies of Novel Antituberculosis Agents
This study is working on new medicines to help fight tuberculosis, especially the tough strains that don't respond to regular treatments, so that patients can have better options for getting better.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Notre Dame NIH-funded |
| Lab location | 1 site (Notre Dame, United States) |
| Project ID | NIH-10888366 on NIH RePORTER |
What this research studies
This research focuses on creating novel antituberculosis agents to combat the growing problem of drug-resistant tuberculosis. The team is investigating specific compounds that target critical components of the Mycobacterium tuberculosis bacteria, aiming to enhance their effectiveness against various strains, including multi-drug resistant types. By advancing promising candidates through laboratory evaluations and preparing them for clinical trials, the research seeks to provide new options for patients suffering from this serious infectious disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with tuberculosis, especially those with multi-drug resistant or extensively drug-resistant forms of the disease.
Not a fit: Patients with non-infectious conditions or those without tuberculosis will not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for tuberculosis, particularly for patients with drug-resistant strains.
How similar studies have performed: Previous research has shown promise in developing new antituberculosis agents, indicating that this approach has potential for success.
Where this research is happening
Notre Dame, United States
- University of Notre Dame — Notre Dame, United States (Active)
Researchers
- Principal investigator: Miller, Marvin J — University of Notre Dame
- Study coordinator: Miller, Marvin J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.