Developing new treatments for respiratory infections using nanoformulations
Official title: Nanoformulations for Respiratory Infections
Funded at James a. Haley VA Medical Center · NIH-10923474 · Data updated 2026-11-12
This study is working on a new nasal treatment to help fight respiratory viruses like COVID-19 and RSV, especially for older adults who are more vulnerable, by using tiny particles to deliver medicine directly to the lungs and boost the immune system.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | James a. Haley VA Medical Center NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | October 1, 2024 |
| Project end | September 30, 2028 |
| Funding year | 2025 |
| NIH project number | 1I01BX006456-01A1 |
| Project ID | NIH-10923474 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are elderly individuals aged 65 and older who are at risk for severe respiratory infections.
✕Less likely to help
Patients under the age of 65 or those without a history of severe respiratory infections may not benefit from this research.
What this research studies
This research focuses on creating innovative antiviral treatments for respiratory infections, particularly targeting viruses like SARS-CoV-2 and RSV. The approach involves developing a specialized intranasal nanoformulation that utilizes liposomes to deliver therapeutic agents directly to the respiratory system. By incorporating specific compounds that can enhance the immune response and inhibit viral replication, the research aims to provide a more effective treatment option for patients, especially the elderly who are at higher risk. The methodology includes the use of advanced nanotechnology to ensure sustained release of the therapeutic agents.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for severe respiratory infections, potentially reducing hospitalizations and improving survival rates among vulnerable populations.
How similar studies have gone: Previous research has shown promise in using nanotechnology for drug delivery in respiratory infections, indicating potential for success in this novel approach.
Where this research is happening
-
James a. Haley VA Medical Center
Tampa, United States Active
Researchers
- Principal investigator: Mohapatra, Shyam S — James a. Haley VA Medical Center
- Study coordinator: Mohapatra, Shyam S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.