Developing new treatments for pancreatic cancer using pig models
Porcine Platforms For Technology Development In Pancreatic Cancer
This study is testing a new way to find better treatments for pancreatic cancer using a special pig model that acts like human cancer, so that researchers can see how well new therapies work before they reach patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-11027550 on NIH RePORTER |
What this research studies
This research aims to create a more effective platform for testing new therapies and devices for pancreatic cancer by using a specially designed pig model. The study will focus on the KRAS/p53 Oncopig, which closely mimics human pancreatic cancer biology, allowing researchers to evaluate the effectiveness of novel treatments and imaging technologies. By utilizing this larger animal model, the research seeks to improve the predictability of treatment outcomes compared to traditional mouse models. Patients may benefit from advancements in treatment options that are better tailored to human responses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with advanced pancreatic cancer who are seeking innovative treatment options.
Not a fit: Patients with early-stage pancreatic cancer or those not eligible for experimental therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for pancreatic cancer, improving patient outcomes.
How similar studies have performed: Previous research using animal models for cancer treatment has shown promise, suggesting that this approach could yield valuable insights, although the specific use of porcine models for pancreatic cancer is relatively novel.
Where this research is happening
Omaha, United States
- University of Nebraska Medical Center — Omaha, United States (Active)
Researchers
- Principal investigator: Hollingsworth, Michael a. — University of Nebraska Medical Center
- Study coordinator: Hollingsworth, Michael a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.