Developing new treatments for heart and muscle injuries in older veterans
Official title: BLRD Research Career Scientist Award Application
Funded at Veterans Admin Palo Alto Health Care Sys · NIH-11103134 · Data updated 2026-11-12
This study is exploring new ways to help older veterans heal better from heart and muscle injuries by looking at how certain signals in the body affect healing, with the hope of improving their recovery and overall quality of life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Admin Palo Alto Health Care Sys NIH-funded |
| Lab location | 1 site (Palo Alto, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| NIH project number | 5IK6BX006309-03 |
| Project ID | NIH-11103134 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are veterans aged 65 and older who are experiencing cardiovascular diseases or traumatic muscle injuries.
✕Less likely to help
Patients who are younger than 65 or do not have cardiovascular or muscle injuries may not benefit from this research.
What this research studies
This research focuses on creating innovative therapies to enhance tissue regeneration and restore function in cardiovascular and skeletal muscle injuries, particularly in veterans aged 65 and older. The approach involves studying how biochemical and biomechanical signals in the extracellular matrix influence cell behavior and tissue function. By using engineered skeletal muscle that mimics natural muscle structure and vascularization, the research aims to improve recovery outcomes for veterans suffering from these conditions. The ultimate goal is to reduce mortality and enhance the quality of life for older veterans facing these health challenges.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery and quality of life for older veterans with cardiovascular and muscle injuries.
How similar studies have gone: Previous research has shown promise in using engineered tissues for regenerative medicine, indicating potential success for this novel approach.
Where this research is happening
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Veterans Admin Palo Alto Health Care Sys
Palo Alto, United States Active
Researchers
- Principal investigator: Huang, Ngan F. — Veterans Admin Palo Alto Health Care Sys
- Study coordinator: Huang, Ngan F.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.