Developing new treatments for endometriosis pain without hormones
Discovery and development of potent inhibitors of Jun N-terminal kinase for non-hormonal treatment of endometriosis and associated pain
['FUNDING_R01'] · BAYLOR COLLEGE OF MEDICINE · NIH-11168709
This study is looking for new non-hormonal treatments for endometriosis by developing special medications that can help reduce the growth of painful lesions, and it's designed for women who are dealing with this condition.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11168709 on ClinicalTrials.gov |
What this research studies
This research focuses on finding effective non-hormonal treatments for endometriosis, a painful condition affecting many women. The team is working on creating specific inhibitors that target Jun N-terminal kinase (JNK), which plays a role in the disease's progression. By interrupting certain biological pathways, the goal is to reduce the growth of endometriosis lesions without affecting hormone levels or the normal endometrial tissue. The research involves collaboration among experts in reproductive biology, immunology, and medicinal chemistry to ensure a comprehensive approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with endometriosis who are seeking non-hormonal treatment options.
Not a fit: Patients who have not been diagnosed with endometriosis or those who are currently receiving effective hormonal treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new, effective treatment option for patients suffering from endometriosis and its associated pain.
How similar studies have performed: Previous research has shown promising results with similar approaches targeting non-hormonal pathways in endometriosis treatment.
Where this research is happening
HOUSTON, UNITED STATES
- BAYLOR COLLEGE OF MEDICINE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MONSIVAIS, DIANA — BAYLOR COLLEGE OF MEDICINE
- Study coordinator: MONSIVAIS, DIANA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.