Developing new treatments for COVID-19

Development of Host- Oriented Therapeutics Targeting Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2),

['FUNDING_OTHER'] · FOX CHASE CHEMICAL DIVERSITY CENTER, INC · NIH-10688262

This study is working on new medicines that can help fight COVID-19 by blocking the virus from spreading in the body, which could lead to better treatments for patients.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorFOX CHASE CHEMICAL DIVERSITY CENTER, INC (nih funded)
Locations1 site (DOYLESTOWN, UNITED STATES)
Trial IDNIH-10688262 on ClinicalTrials.gov

What this research studies

This research focuses on creating small molecule compounds that target the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19. The approach involves understanding how the virus interacts with specific host proteins to facilitate its spread and developing antiviral agents that can disrupt these interactions. By targeting these mechanisms, the research aims to provide effective treatments against SARS-CoV-2 and its emerging variants. Patients may benefit from new antiviral therapies that could reduce the severity of COVID-19 infections.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who are at risk of severe COVID-19 infection or those who have tested positive for SARS-CoV-2.

Not a fit: Patients who are not infected with SARS-CoV-2 or those who have already recovered from COVID-19 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new antiviral treatments that significantly improve outcomes for patients infected with COVID-19.

How similar studies have performed: Other research has shown promise in developing antiviral agents targeting similar mechanisms in viral infections, indicating a potential for success in this novel approach.

Where this research is happening

DOYLESTOWN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.