Developing new treatments for anxiety using sterol carrier protein inhibitors

Development of sterol carrier protein 2 inhibitors as anxiolytics

NIH-funded research Medical College of Wisconsin · NIH-11126763

This study is exploring a new way to help people with anxiety by blocking a specific protein in the body, which could lead to treatments that work better and have fewer side effects than regular anxiety medications.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical College of Wisconsin NIH-funded
Lab location1 site (Milwaukee, United States)
Project IDNIH-11126763 on NIH RePORTER

What this research studies

This research focuses on finding new ways to treat anxiety disorders by targeting a specific protein called sterol carrier protein-2 (SCP-2). The approach involves inhibiting SCP-2 to enhance the signaling of natural compounds in the body that can help reduce anxiety. By doing so, the researchers aim to create a treatment that has fewer side effects compared to traditional anxiety medications. The study will involve both laboratory experiments and potential clinical trials to evaluate the effectiveness of these new inhibitors.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing anxiety disorders.

Not a fit: Patients who do not have anxiety disorders or those who are currently receiving effective treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer treatments for individuals suffering from anxiety disorders.

How similar studies have performed: Previous research has shown promise in using similar approaches to enhance cannabinoid receptor signaling for anxiety treatment, indicating potential for success in this novel approach.

Where this research is happening

Milwaukee, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.