Developing new treatments for a rare type of pancreatic cancer.
New Therapuetics for Pancreatic Cancer
This study is looking at a rare type of pancreatic cancer called adenosquamous cancer to understand its unique traits and find new ways to treat it, since there aren’t any standard treatments available right now.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11074624 on NIH RePORTER |
What this research studies
This research focuses on Adenosquamous cancer of the pancreas (ASCP), a rare and aggressive subtype of pancreatic cancer. The team will create a large collection of ASCP models to study their unique genomic and epigenomic characteristics compared to the more common pancreatic ductal adenocarcinoma (PDAC). By identifying specific epigenetic features, the researchers aim to discover new therapeutic targets that could help slow down or stop the growth of ASCP cells. This work is crucial as there are currently no established standard treatments for this subtype.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Adenosquamous cancer of the pancreas.
Not a fit: Patients with other types of pancreatic cancer, such as pancreatic ductal adenocarcinoma, may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of targeted therapies that significantly improve outcomes for patients with ASCP.
How similar studies have performed: While research on pancreatic cancer is ongoing, this specific approach focusing on ASCP is relatively novel and has not been extensively tested.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Fernandez-Zapico, Martin Ernesto — Mayo Clinic Rochester
- Study coordinator: Fernandez-Zapico, Martin Ernesto
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.