Developing new tools to analyze single cell genomic data from multiple samples
Official title: Analytical Infrastructure for Multiple Sample Single Cell Genomic Data
Funded at Johns Hopkins University · NIH-10989329 · Data updated 2026-11-12
This study is working on new ways to look at individual cells to help us understand how they behave in health and disease, especially in tricky situations like tumors, so that patients can get better insights into their conditions and how they might respond to treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 1, 2024 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $361,069 |
| NIH project number | 1R01HG013409-01A1 |
| Project ID | NIH-10989329 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with conditions that involve complex cellular interactions, such as cancer or developmental disorders.
✕Less likely to help
Patients with stable, non-complex conditions that do not involve significant cellular heterogeneity may not benefit from this research.
What this research studies
This research focuses on advancing single cell genomic technologies that can analyze various biological data from individual cells. It aims to create new analytical methods and software tools to better understand how different samples vary and how these variations relate to patient characteristics. By addressing challenges in analyzing multi-sample genomic data, the project seeks to enhance our understanding of cellular behavior in health and disease, particularly in complex environments like tumors. Patients may benefit from improved insights into disease progression and treatment responses.
Why it matters
Potential benefit: If successful, this research could lead to more precise and personalized medical treatments based on individual cellular responses.
How similar studies have gone: Other research has shown success in using single cell genomic technologies to uncover insights into cellular behavior, indicating that this approach has a strong foundation.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Ji, Hongkai — Johns Hopkins University
- Study coordinator: Ji, Hongkai
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.