Developing new technology for analyzing large biomolecules
Official title: HIGHLY SELECTIVE MACROBIOMOLECULAR ISOLATION, SOFT-LANDING AND CHARACTERIZATION USING STRUCTURES FOR LOSSLESS ION MANIPULATIONS
Funded at Battelle Pacific Northwest Laboratories · NIH-10895478 · Data updated 2026-11-12
This study is working on new technology to quickly and accurately analyze important molecules in our bodies, which could help doctors diagnose and treat health conditions better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Pacific Northwest Laboratories NIH-funded |
| Lab location | 1 site (Richland, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $450,205 |
| NIH project number | 5R01CA283818-02 |
| Project ID | NIH-10895478 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with conditions related to biomolecular dysfunction or diseases that involve large biomolecules.
✕Less likely to help
Patients with conditions unrelated to biomolecular analysis or those who do not have large biomolecules involved in their disease processes may not benefit from this research.
What this research studies
This research focuses on creating advanced technology to rapidly and accurately profile large biomolecules, which are essential for understanding various biological processes. By utilizing a novel device that combines ion mobility and mass spectrometry, the project aims to enhance the ability to analyze the mass and structure of these complex molecules. Patients may benefit from this research as it could lead to improved diagnostic tools and treatments based on a better understanding of biomolecular behavior.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in the diagnosis and treatment of diseases by providing detailed insights into biomolecular structures.
How similar studies have gone: Other research has shown success in developing advanced mass spectrometry techniques for small molecules, but this approach for large biomolecules is relatively novel.
Where this research is happening
-
Battelle Pacific Northwest Laboratories
Richland, United States Active
Researchers
- Principal investigator: Garimella, Sandilya — Battelle Pacific Northwest Laboratories
- Study coordinator: Garimella, Sandilya
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.