Developing new technologies to study kidney disease at the cellular level
Official title: Development Core
Funded at Washington University · NIH-10915656 · Data updated 2026-11-12
This study is looking at how kidney cells work and interact with each other to help us better understand chronic kidney disease, so we can find new ways to improve treatment and care for people with this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $273,772 |
| NIH project number | 5U54DK137332-02 |
| Project ID | NIH-10915656 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with chronic kidney disease or those at risk of developing it.
✕Less likely to help
Patients with acute kidney injury or those without any kidney-related conditions may not benefit from this research.
What this research studies
This research focuses on advancing single-cell technologies to better understand chronic kidney disease (CKD) by examining how cells behave and interact within their tissue environment. It aims to overcome current limitations of single-cell RNA sequencing, which often loses important spatial information about cells. By developing new protocols and computational tools, the project seeks to provide insights into the cellular processes involved in kidney injury and repair. This work will support kidney research and improve our understanding of CKD at a fundamental level.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for chronic kidney disease.
How similar studies have gone: Other research has shown promise in using advanced single-cell technologies to study various diseases, indicating that this approach could yield valuable insights into chronic kidney disease as well.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Humphreys, Benjamin D. — Washington University
- Study coordinator: Humphreys, Benjamin D.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.