Developing new technologies for vaccines against infectious diseases
Official title: NIAID VRC NUCLEIC ACID AND LIPID TECHNOLOGY DEVELOPMENT
Funded at Leidos Biomedical Research, INC. · NIH-10942128 · Data updated 2026-11-12
This study is working on new ways to make vaccines using DNA and RNA to help fight infections like COVID-19, HIV, and the flu, so that people can get better and faster protection when outbreaks happen.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Leidos Biomedical Research, INC. NIH-funded |
| Lab location | 1 site (Frederick, United States) |
| Project start | September 15, 2023 |
| Project end | September 14, 2028 |
| Funding year | 2023 |
| Award (this year) | $7,090,787 |
| NIH project number | 75N91019D00024-0-759102300018-1 |
| Project ID | NIH-10942128 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit include individuals at risk for infectious diseases such as COVID-19, HIV, and influenza.
✕Less likely to help
Patients who are not at risk for infectious diseases or those who have already been vaccinated may not receive direct benefits from this research.
What this research studies
This research focuses on creating and testing new vaccine technologies, particularly using nucleic acids like DNA and RNA, to combat infectious diseases. It aims to enhance the rapid manufacturing processes for vaccines, especially in response to outbreaks like COVID-19. By developing lipid nanoparticle formulations, the research seeks to improve the delivery and effectiveness of mRNA vaccines for various infectious diseases, including HIV and influenza. Patients may benefit from more effective and rapidly available vaccines as a result of this work.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective vaccines that can be rapidly deployed during infectious disease outbreaks.
How similar studies have gone: Previous research has shown success in developing mRNA vaccines for COVID-19, indicating that similar approaches may be effective for other infectious diseases.
Where this research is happening
-
Leidos Biomedical Research, INC.
Frederick, United States Active
Researchers
- Principal investigator: Coleman, Victoria — Leidos Biomedical Research, INC.
- Study coordinator: Coleman, Victoria
Related research
Other NIH-funded projects on the same topics.
-
Improving public health responses to COVID-19 through standardized testing.
This study is looking to improve how we fight COVID-19 by testing blood samples to see if people have had the virus, and it’s designed for anyone interested in better ways to manage the disease.
-
Creating a large library of cancer models for research use
This study is creating a collection of new cancer models to help researchers and companies find better ways to treat cancer, making it easier for everyone to work together and share ideas.
-
Advancing global cancer control through data analysis and international collaboration
This study is all about helping countries around the world work better together to fight cancer by sharing important information and training scientists, especially in places that need extra support.
-
Support for HIV and HPV cancer prevention clinical trials in the Americas
This study is working on new vaccines and treatments to help prevent cancers related to HIV and HPV, making sure that patients in the US, Latin America, and the Caribbean can access better options as these exciting trials move forward.
-
Development and production of clinical-grade biopharmaceuticals
This study is all about making safe and effective new medicines, like vaccines and treatments for various conditions, so that patients can have access to the latest therapies that meet high-quality standards.
-
Understanding the immune response to COVID-19
This study is looking for ways to improve COVID-19 testing and understand how our immune system fights the virus, and you can help by sharing samples to make these tests better for everyone.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.