Developing new technologies for vaccines against infectious diseases

NIAID VRC NUCLEIC ACID AND LIPID TECHNOLOGY DEVELOPMENT

NIH-funded research Leidos Biomedical Research, INC. · NIH-10942128

This study is working on new ways to make vaccines using DNA and RNA to help fight infections like COVID-19, HIV, and the flu, so that people can get better and faster protection when outbreaks happen.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLeidos Biomedical Research, INC. NIH-funded
Lab location1 site (Frederick, United States)
Project IDNIH-10942128 on NIH RePORTER

What this research studies

This research focuses on creating and testing new vaccine technologies, particularly using nucleic acids like DNA and RNA, to combat infectious diseases. It aims to enhance the rapid manufacturing processes for vaccines, especially in response to outbreaks like COVID-19. By developing lipid nanoparticle formulations, the research seeks to improve the delivery and effectiveness of mRNA vaccines for various infectious diseases, including HIV and influenza. Patients may benefit from more effective and rapidly available vaccines as a result of this work.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit include individuals at risk for infectious diseases such as COVID-19, HIV, and influenza.

Not a fit: Patients who are not at risk for infectious diseases or those who have already been vaccinated may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of more effective vaccines that can be rapidly deployed during infectious disease outbreaks.

How similar studies have performed: Previous research has shown success in developing mRNA vaccines for COVID-19, indicating that similar approaches may be effective for other infectious diseases.

Where this research is happening

Frederick, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Infectious Disease PathwayInfectious DiseasesInfectious Disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.