Developing new statistical tools for understanding the microbiome
Official title: Collaborative Research: DMS/NIGMS 2: New statistical methods, theory, and software for microbiome data
Funded at Pennsylvania State University, the · NIH-10919839 · Data updated 2026-11-12
This study is working on new ways to analyze tiny organisms in our bodies to better understand how they affect our health, which could help create better treatments for conditions like asthma and autism.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project start | September 5, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $303,860 |
| NIH project number | 5R01GM152812-02 |
| Project ID | NIH-10919839 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with conditions such as asthma, autism, or other disorders potentially influenced by microbiome health.
✕Less likely to help
Patients with conditions unrelated to microbiome health or those not participating in the studies may not receive any benefit from this research.
What this research studies
This research focuses on creating advanced statistical methods and software to analyze microbiome data, particularly from high-throughput sequencing technologies like 16S rRNA gene sequencing. By addressing the computational challenges associated with this complex data, the project aims to improve our understanding of how microbial communities impact human health and disease. Patients may benefit from these insights as they could lead to more effective microbiome-based therapies for conditions such as asthma and autism. The research will involve collaboration across large studies to ensure the methods developed are robust and applicable in real-world settings.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and interventions for various health conditions linked to the microbiome.
How similar studies have gone: Other research has shown promise in using statistical methods to analyze microbiome data, indicating that this approach could lead to significant advancements in the field.
Where this research is happening
-
Pennsylvania State University, the
University Park, United States Active
Researchers
- Principal investigator: Xue, Lingzhou — Pennsylvania State University, the
- Study coordinator: Xue, Lingzhou
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.