Developing new methods to identify proteins and their modifications at a single-molecule level.
Chemistry for next-generation single-molecule fluorosequencing technology 2.0.
This study is working on new ways to find tiny amounts of important proteins in the body that can help us understand diseases like cancer better, which could lead to new tests and treatments for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10645898 on NIH RePORTER |
What this research studies
This research focuses on advancing techniques to identify proteins and their modifications, known as post-translational modifications (PTMs), at a single-molecule level. By creating new chemical methods, the project aims to improve the detection of low-abundance proteins that play critical roles in diseases like cancer. This could lead to better understanding of biological processes and the discovery of new biomarkers for disease diagnosis and treatment. The approach combines organic chemistry with biological analysis to enhance precision medicine.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cancer or other diseases where protein mutations and modifications are significant.
Not a fit: Patients with conditions unrelated to protein mutations or those not requiring advanced diagnostic techniques may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in cancer diagnostics and treatment by providing more accurate identification of protein variants and their functions.
How similar studies have performed: Previous research has shown promise in developing single-molecule techniques for protein analysis, indicating potential for success in this novel approach.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Raj, Monika — Emory University
- Study coordinator: Raj, Monika
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.