Developing new methods to create important organic compounds
Official title: New Methods for Nitrogen and Oxygen Heterocycle Synthesis
Funded at State University of New York at Buffalo · NIH-11090434 · Data updated 2026-11-12
This study is exploring new ways to make important small molecules that can help develop better medicines, using a special technique that reduces waste, with the goal of finding new treatments for different health conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Buffalo NIH-funded |
| Lab location | 1 site (Amherst, United States) |
| Project start | July 1, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $388,751 |
| NIH project number | 5R35GM153290-02 |
| Project ID | NIH-11090434 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with conditions that could be treated by new pharmaceuticals derived from these organic compounds.
✕Less likely to help
Patients with conditions that are not addressed by the types of drugs produced from these organic compounds may not receive any benefit from this research.
What this research studies
This research focuses on creating efficient methods for synthesizing small organic molecules that are crucial in pharmaceutical development. By using innovative copper-catalyzed reactions, the project aims to produce chiral compounds that are essential for drug discovery while minimizing waste. The approach emphasizes the synthesis of complex molecules that could lead to new bioactive natural products and pharmaceuticals, potentially improving treatment options for various diseases.
Why it matters
Potential benefit: If successful, this research could lead to more effective and sustainable methods for producing drugs, ultimately benefiting patients through improved therapies.
How similar studies have gone: Other research has shown success in developing efficient synthesis methods for organic compounds, indicating that this approach has potential for significant advancements.
Where this research is happening
-
State University of New York at Buffalo
Amherst, United States Active
Researchers
- Principal investigator: Chemler, Sherry R — State University of New York at Buffalo
- Study coordinator: Chemler, Sherry R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.