Developing new methods to create important nitrogen-containing compounds for medications

Construction of Heteroarenes Through Single Atom Insertion Strategies

['FUNDING_OTHER'] · UNIVERSITY OF CHICAGO · NIH-10876486

This study is exploring new ways to make important building blocks for medicines, which could lead to better and more effective drugs for patients like you.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CHICAGO (nih funded)
Locations1 site (CHICAGO, UNITED STATES)
Trial IDNIH-10876486 on ClinicalTrials.gov

What this research studies

This research focuses on creating new strategies and reagents to synthesize nitrogenous heterocycles, which are crucial components in many medications. By utilizing single-atom insertion reactions, the project aims to improve the efficiency and effectiveness of producing these compounds, such as pyridines and pyrimidines. The approach combines innovative chemical reactions to transform existing structures into new medicinally relevant compounds, potentially enhancing drug development processes. Patients may benefit from new and improved medications that arise from these advancements in medicinal chemistry.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would be individuals with conditions that could be treated by new nitrogenous heterocyclic drugs.

Not a fit: Patients who are not affected by conditions treatable by nitrogen-containing medications may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of new medications that are more effective in treating various conditions.

How similar studies have performed: Previous research has shown success in developing similar synthetic strategies for creating medicinal compounds, indicating a promising potential for this approach.

Where this research is happening

CHICAGO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.