Developing new methods to create complex molecules for medical use
Official title: Iterative Cyclization Strategies for Complex Molecule Synthesis
Funded at University of Rochester · NIH-11061120 · Data updated 2026-11-12
This study is all about finding new ways to create important molecules that could help develop better medicines for patients, focusing on making them easier to produce and study for their potential health benefits.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | April 1, 2024 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $284,130 |
| NIH project number | 5R01GM153936-02 |
| Project ID | NIH-11061120 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with conditions that could be treated by novel chemical therapies derived from the synthesized molecules.
✕Less likely to help
Patients with conditions that are not addressed by the specific therapeutic applications of the synthesized molecules may not receive any benefit from this research.
What this research studies
This research focuses on creating innovative strategies for synthesizing complex molecules that have potential bioactivity and bioavailability. By developing efficient methods for forming carbon-carbon bonds, chemists aim to produce biologically relevant compounds that can be used in chemical therapies. The project will explore the synthesis of cyclic structures from simple precursors, enhancing the ability to study these compounds for their therapeutic applications. Patients may benefit from the resulting advancements in drug development and treatment options.
Why it matters
Potential benefit: If successful, this research could lead to the development of new and more effective therapies for various medical conditions.
How similar studies have gone: Other research has shown success in developing new synthetic methods for complex molecules, indicating a promising avenue for further exploration.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Frontier, Alison J — University of Rochester
- Study coordinator: Frontier, Alison J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.