Developing new methods to analyze complex biological structures
From complex data to complex structures: new methods for structural biology
['FUNDING_OTHER'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-10877856
This study is working on better ways to look at the tiny structures of biological molecules, which can help us understand how cells work and lead to the development of new and more effective treatments for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-10877856 on ClinicalTrials.gov |
What this research studies
This research focuses on improving techniques for analyzing the structures of biological molecules using advanced imaging methods like X-ray crystallography and cryo-electron microscopy. By enhancing data analysis methods, the project aims to provide clearer insights into cellular processes at the molecular level, which can help validate findings from other biological studies. Additionally, the research seeks to guide the design of new drugs by creating reliable structural models from complex data sets. Patients may benefit from this work as it could lead to more effective treatments based on a better understanding of disease mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions that involve complex cellular processes or those who may require new drug therapies.
Not a fit: Patients with conditions that do not involve molecular or cellular dysfunction may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective drugs and therapies by providing deeper insights into the molecular structures involved in diseases.
How similar studies have performed: Previous research has shown success in using advanced imaging techniques to improve our understanding of biological structures, indicating that this approach has potential for significant advancements.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: OTWINOWSKI, ZBYSZEK — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: OTWINOWSKI, ZBYSZEK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.