Developing new methods to activate and expand T cells for cancer treatment
TR&D Project 1
This study is working on new ways to boost your immune system's T cells to better fight cancer, using special tools that could make treatments easier and more affordable, so patients like you might have access to better immunotherapy options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11134614 on NIH RePORTER |
What this research studies
This research focuses on creating advanced platforms to activate and expand T cells specifically targeting cancer cells. By engineering artificial antigen-presenting cells and biodegradable microparticles, the project aims to enhance the immune response against tumors while simplifying the process and reducing costs. The study will explore how to optimize these platforms to improve the effectiveness of both CD4+ and CD8+ T cells in fighting cancer. Patients may benefit from new immunotherapy options that are more efficient and effective.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with cancer who may benefit from enhanced T cell therapies.
Not a fit: Patients with non-cancerous conditions or those who do not respond to immunotherapy may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and accessible cancer immunotherapies for patients.
How similar studies have performed: Previous research has shown promise in using engineered antigen-presenting cells for immunotherapy, indicating potential success for this novel approach.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Schneck, Jonathan P — Johns Hopkins University
- Study coordinator: Schneck, Jonathan P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.