Developing new methods for creating PET imaging tracers
Novel Approaches to 11C- and 18F-Trifluoromethylation for PET Tracer Development
['FUNDING_R01'] · UNIVERSITY OF CINCINNATI · NIH-11129012
This study is working on making better PET scans, which help doctors see what's happening inside your body, by developing new ways to improve the imaging process, so patients can get more accurate diagnoses and treatment plans.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CINCINNATI (nih funded) |
| Locations | 1 site (CINCINNATI, UNITED STATES) |
| Trial ID | NIH-11129012 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the development of PET imaging tracers, which are essential for non-invasive visualization of biological processes in the body. The team aims to create new methods for introducing radiolabeled trifluoromethyl groups into molecules, which will enhance the effectiveness of PET scans. By collaborating with experts in chemistry and radiopharmaceutical sciences, the project seeks to establish innovative techniques that can be applied to various biological targets. Patients may benefit from more accurate and effective imaging techniques that can lead to better diagnosis and treatment planning.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals requiring advanced imaging techniques for conditions related to COX-1, MAO-B, and other biological targets.
Not a fit: Patients who do not require PET imaging or have conditions unrelated to the biological targets being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more precise PET imaging, improving diagnosis and treatment monitoring for various medical conditions.
How similar studies have performed: While the approach to trifluoromethylation is innovative, similar research has shown promise in enhancing PET tracer development, indicating potential for success.
Where this research is happening
CINCINNATI, UNITED STATES
- UNIVERSITY OF CINCINNATI — CINCINNATI, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIU, WEI — UNIVERSITY OF CINCINNATI
- Study coordinator: LIU, WEI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.