Developing new methods for creating important chemical compounds
Official title: Halogenase Inspired Chemical Catalysis and Methods
Funded at University of Toledo · NIH-10875838 · Data updated 2026-11-12
This study is working on making special molecules that can help create new medicines and treatments, using easier and more efficient methods, which could eventually lead to better health options for patients.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Toledo NIH-funded |
| Lab location | 1 site (Toledo, United States) |
| Project start | September 1, 2020 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $458,584 |
| NIH project number | 2R15GM139156-02 |
| Project ID | NIH-10875838 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals who require new or improved pharmaceutical treatments derived from chiral amino functionalized molecules.
✕Less likely to help
Patients who are not seeking new pharmaceutical treatments or who do not have conditions that could be addressed by these compounds may not benefit from this research.
What this research studies
This research focuses on creating chiral amino functionalized molecules, which are essential in various bioactive compounds and organic synthesis. The team aims to develop innovative catalytic processes that utilize readily available chemical feedstocks to synthesize these important molecules efficiently. By introducing new catalytic methods, such as chiral hypervalent iodine and halonium catalysis, the research seeks to overcome existing challenges in achieving the desired chemical reactions. Patients may benefit indirectly from this research as it could lead to advancements in pharmaceuticals and treatments derived from these compounds.
Why it matters
Potential benefit: If successful, this research could lead to more efficient production of pharmaceuticals and other bioactive compounds, potentially improving treatment options for patients.
How similar studies have gone: While the specific methods being explored may be novel, there is a history of success in similar catalytic approaches in organic synthesis.
Where this research is happening
-
University of Toledo
Toledo, United States Active
Researchers
- Principal investigator: Li, Wei — University of Toledo
- Study coordinator: Li, Wei
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.