Developing new methods for creating complex medicinal molecules
Metallacycle-mediated coupling in stereoselective synthesis
This study is looking at new ways to create complex molecules that could help develop better treatments for diseases like multiple myeloma, aiming to find new non-opioid pain relief options and targeted cancer therapies that could benefit patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project ID | NIH-10748298 on NIH RePORTER |
What this research studies
This research focuses on innovative techniques in organic chemistry to synthesize complex molecules that may have significant medicinal and biological properties. The team is exploring various chemical reactions, including metallacycle-mediated cross-coupling and other stereoselective methods, to create compounds that could lead to new treatments for diseases like multiple myeloma. By advancing the fundamental principles of organic synthesis, the research aims to enable the discovery of new drugs and therapies. Patients may benefit from the development of novel non-opioid analgesics and targeted therapies for specific cancers.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals diagnosed with multiple myeloma or those seeking alternative pain management options.
Not a fit: Patients with conditions unrelated to the focus of this research, such as acute infections or non-cancerous ailments, may not receive any benefit.
Why it matters
Potential benefit: If successful, this research could lead to the development of new, effective treatments for multiple myeloma and other conditions.
How similar studies have performed: Previous research in organic synthesis has shown success in developing new therapeutic agents, indicating that this approach has the potential for significant breakthroughs.
Where this research is happening
Hanover, United States
- Dartmouth College — Hanover, United States (Active)
Researchers
- Principal investigator: Micalizio, Glenn C — Dartmouth College
- Study coordinator: Micalizio, Glenn C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.