Developing new methods for creating carbon-11 labeled PET imaging agents
Fluoride-Mediated Desilylative Radiosynthesis of 11C-Labeled PET Tracers
['FUNDING_R01'] · STATE UNIVERSITY NEW YORK STONY BROOK · NIH-11015844
This study is working on making a special type of imaging tool that helps doctors see inside the body more clearly, which can improve how we diagnose and understand different diseases, especially since it can be used multiple times in one day.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STATE UNIVERSITY NEW YORK STONY BROOK (nih funded) |
| Locations | 1 site (STONY BROOK, UNITED STATES) |
| Trial ID | NIH-11015844 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the synthesis of carbon-11 labeled PET tracers, which are crucial for advanced imaging techniques used in diagnosing and studying various diseases. By utilizing a novel fluoride-mediated desilylative approach, the project aims to create these tracers more efficiently and with higher purity. This could allow for more accurate imaging and better understanding of biological processes in patients. The short half-life of carbon-11 enables multiple scans in a single day, making it ideal for both clinical and research applications.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals requiring advanced imaging for conditions such as cancer or cardiovascular diseases.
Not a fit: Patients who do not require PET imaging or have conditions that do not benefit from this type of diagnostic approach may not receive any benefit.
Why it matters
Potential benefit: If successful, this research could enhance the accuracy of PET imaging, leading to better diagnosis and treatment monitoring for patients.
How similar studies have performed: Previous research has shown promise in developing new radiolabeling techniques, indicating that this approach could lead to significant advancements in PET imaging.
Where this research is happening
STONY BROOK, UNITED STATES
- STATE UNIVERSITY NEW YORK STONY BROOK — STONY BROOK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: QU, WENCHAO — STATE UNIVERSITY NEW YORK STONY BROOK
- Study coordinator: QU, WENCHAO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.