Developing new medications to treat opioid use disorder
Mu Opioid Receptor Modulator Development to Treat Opioid Use Disorder
This study is looking for new medications to help people who are dealing with opioid use disorder, aiming to make treatments more effective and with fewer side effects.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-11006291 on NIH RePORTER |
What this research studies
This research focuses on creating new medications to help individuals struggling with opioid use disorder, a significant public health crisis in the United States. The team is investigating novel compounds that target the mu opioid receptor, aiming to enhance therapeutic effects while minimizing side effects. The research involves preclinical studies to validate the effectiveness and safety of these new drug candidates. By expanding the library of potential medications, the project seeks to improve treatment options for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with opioid use disorder who are seeking new treatment options.
Not a fit: Patients who are not struggling with opioid use disorder or those who have not responded to previous treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatments for individuals with opioid use disorder.
How similar studies have performed: Other research has shown promise in developing new medications for opioid use disorder, but this approach focuses on novel compounds that have not yet been tested in clinical settings.
Where this research is happening
Richmond, United States
- Virginia Commonwealth University — Richmond, United States (Active)
Researchers
- Principal investigator: Zhang, Yan — Virginia Commonwealth University
- Study coordinator: Zhang, Yan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.